8ULK

Prefusion RSV F bound by neutralizing antibody 1G12

Summary for 8ULK

• Entry DOI: 10.2210/pdb8ulk/pdb
• Descriptor: Fusion glycoprotein F2, 1G12 Fab heavy chain, 1G12 Fab light chain, ... (4 entities in total)
• Functional Keywords: rsv, antibody, neutralizing, pre-fusion, glycoprotein, antiviral, viral protein-immune system complex, viral protein/immune system
• Biological source: Human respiratory syncytial virus A2; More
• Total number of polymer chains: 12
• Total formula weight: 307235.46

Authors

Harshbarger, W.D.,Andreano, E.,Malito, E. (deposition date: 2023-10-16, release date: 2024-11-06)

• Primary citation: Xian, Y.,Andreano, E.,Tian, S.,Phung, E.,Garbinski, L.,Biancucci, M.,Lofano, G.,Mallett, C.P.,Balsaraf, A.,Huang, Y.,Buricchi, F.,Finco, O.,Rappuoli, R.,Bottomley, M.J.,Chandramouli, S.,Warter, L.,Williams, J.,Malito, E.,Harshbarger, W.D.; Structural and functional properties of monoclonal and vaccine-induced antibodies targeting epitopes of emerging RSV variants; To be published,

Experimental method

X-RAY DIFFRACTION (4.28 Å)