8ULK

Prefusion RSV F bound by neutralizing antibody 1G12

8ULK の概要

• エントリーDOI: 10.2210/pdb8ulk/pdb
• 分子名称: Fusion glycoprotein F2, 1G12 Fab heavy chain, 1G12 Fab light chain, ... (4 entities in total)
• 機能のキーワード: rsv, antibody, neutralizing, pre-fusion, glycoprotein, antiviral, viral protein-immune system complex, viral protein/immune system
• 由来する生物種: Human respiratory syncytial virus A2; 詳細
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 307235.46

構造登録者

Harshbarger, W.D.,Andreano, E.,Malito, E. (登録日: 2023-10-16, 公開日: 2024-11-06)

• 主引用文献: Xian, Y.,Andreano, E.,Tian, S.,Phung, E.,Garbinski, L.,Biancucci, M.,Lofano, G.,Mallett, C.P.,Balsaraf, A.,Huang, Y.,Buricchi, F.,Finco, O.,Rappuoli, R.,Bottomley, M.J.,Chandramouli, S.,Warter, L.,Williams, J.,Malito, E.,Harshbarger, W.D.; Structural and functional properties of monoclonal and vaccine-induced antibodies targeting epitopes of emerging RSV variants; To be published,

実験手法

X-RAY DIFFRACTION (4.28 Å)