8UK5
Crystal structure of the bromodomain of human ATAD2B in complex with histone H4S1(ph)K5ac
Summary for 8UK5
Entry DOI | 10.2210/pdb8uk5/pdb |
Descriptor | ATPase family AAA domain-containing protein 2B, Histone H4S1(ph)K5ac (3 entities in total) |
Functional Keywords | bromodomain, epigenetics, chromatin reader domain, protein binding, histone acetylation, peptide binding protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 17166.50 |
Authors | Montgomery, C.,Phillips, M.,Nix, J.C.,Glass, K.C. (deposition date: 2023-10-12, release date: 2024-06-05) |
Primary citation | Phillips, M.,Malone, K.L.,Boyle, B.W.,Montgomery, C.,Kressy, I.A.,Joseph, F.M.,Bright, K.M.,Boyson, S.P.,Chang, S.,Nix, J.C.,Young, N.L.,Jeffers, V.,Frietze, S.,Glass, K.C. Impact of Combinatorial Histone Modifications on Acetyllysine Recognition by the ATAD2 and ATAD2B Bromodomains. J.Med.Chem., 67:8186-8200, 2024 Cited by PubMed: 38733345DOI: 10.1021/acs.jmedchem.4c00210 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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