8UHB

Cryo-EM Structure of the Ro5256390-bound hTA1-Gs heterotrimer signaling complex

8UHB の概要

• エントリーDOI: 10.2210/pdb8uhb/pdb
• EMDBエントリー: 42268
• 分子名称: Soluble cytochrome b562,Beta-2 adrenergic receptor,Trace amine-associated receptor 1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... (6 entities in total)
• 機能のキーワード: gpcr, signaling complex, trace amine-associated receptor, membrane protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 168035.26

構造登録者

Zilberg, G.,Warren, A.L.,Parpounas, A.K.,Wacker, D. (登録日: 2023-10-08, 公開日: 2024-01-10, 最終更新日: 2024-05-01)

• 主引用文献: Zilberg, G.,Parpounas, A.K.,Warren, A.L.,Yang, S.,Wacker, D.; Molecular basis of human trace amine-associated receptor 1 activation.; Nat Commun, 15:108-108, 2024; PubMed: 38168118; DOI: 10.1038/s41467-023-44601-4

実験手法

ELECTRON MICROSCOPY (3.35 Å)