8UGY

Serotonin 1E receptor (5-HT1eR)-Gi1 Complex bound with Mianserin

8UGY の概要

• エントリーDOI: 10.2210/pdb8ugy/pdb
• EMDBエントリー: 42241
• 分子名称: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
• 機能のキーワード: gpcr, signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 128713.51

構造登録者

Zilberg, G.,Warren, A.L.,Wacker, D. (登録日: 2023-10-06, 公開日: 2024-05-01, 最終更新日: 2024-05-08)

• 主引用文献: Zilberg, G.,Parpounas, A.K.,Warren, A.L.,Fiorillo, B.,Provasi, D.,Filizola, M.,Wacker, D.; Structural insights into the unexpected agonism of tetracyclic antidepressants at serotonin receptors 5-HT 1e R and 5-HT 1F R.; Sci Adv, 10:eadk4855-eadk4855, 2024; PubMed: 38630816; DOI: 10.1126/sciadv.adk4855

実験手法

ELECTRON MICROSCOPY (3.31 Å)