8UGS

Cryo-EM structure of bovine phosphodiesterase 6 bound to cGMP

8UGS の概要

• エントリーDOI: 10.2210/pdb8ugs/pdb
• 関連するPDBエントリー: 8UFI 8UGB
• EMDBエントリー: 42234
• 分子名称: Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha, Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta, Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma, ... (6 entities in total)
• 機能のキーワード: phosphodiesterase, gpcr effector enzyme, signaling protein, inhibitor, signaling protein-inhibitor complex, signaling protein/inhibitor
• 由来する生物種: Bos taurus (cattle); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 218840.14

構造登録者

Aplin, C.,Cerione, R.A. (登録日: 2023-10-06, 公開日: 2024-01-17, 最終更新日: 2024-02-07)

• 主引用文献: Aplin, C.,Cerione, R.A.; Probing the mechanism by which the retinal G protein transducin activates its biological effector PDE6.; J.Biol.Chem., 300:105608-105608, 2023; PubMed: 38159849; DOI: 10.1016/j.jbc.2023.105608

実験手法

ELECTRON MICROSCOPY (3.2 Å)