8U8F

GPR3 Orphan G-coupled Protein Receptor in complex with Dominant Negative Gs.

8U8F の概要

• エントリーDOI: 10.2210/pdb8u8f/pdb
• EMDBエントリー: 42023
• 分子名称: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (5 entities in total)
• 機能のキーワード: gpr3, orphan gpcr, gpcr, membrane protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 131533.92

構造登録者

Russell, I.C.,Belousoff, M.J.,Sexton, P. (登録日: 2023-09-17, 公開日: 2024-03-06, 最終更新日: 2024-03-13)

• 主引用文献: Russell, I.C.,Zhang, X.,Bumbak, F.,McNeill, S.M.,Josephs, T.M.,Leeming, M.G.,Christopoulos, G.,Venugopal, H.,Flocco, M.M.,Sexton, P.M.,Wootten, D.,Belousoff, M.J.; Lipid-Dependent Activation of the Orphan G Protein-Coupled Receptor, GPR3.; Biochemistry, 63:625-631, 2024; PubMed: 38376112; DOI: 10.1021/acs.biochem.3c00647

実験手法

ELECTRON MICROSCOPY (3.49 Å)