8U72
Cryo-EM structure of the SPARTA oligomer with guide RNA and target DNA
Summary for 8U72
Entry DOI | 10.2210/pdb8u72/pdb |
EMDB information | 41966 |
Descriptor | RNA (5'-R(P*UP*GP*AP*GP*GP*UP*AP*GP*UP*AP*GP*GP*UP*UP*GP*UP*AP*UP*A)-3'), DNA (5'-D(P*TP*AP*TP*AP*CP*AP*AP*CP*CP*TP*AP*CP*TP*AP*CP*CP*TP*C)-3'), TIR domain-containing protein, ... (6 entities in total) |
Functional Keywords | rna, dna, argonaute, tir, immune system, rna binding protein-rna-dna complex, rna binding protein/rna/dna |
Biological source | Thermoflavifilum thermophilum More |
Total number of polymer chains | 16 |
Total formula weight | 528407.09 |
Authors | Malik, R.,Kottur, J.,Aggarwal, A.K. (deposition date: 2023-09-14, release date: 2024-06-12, Last modification date: 2024-06-19) |
Primary citation | Kottur, J.,Malik, R.,Aggarwal, A.K. Nucleic acid mediated activation of a short prokaryotic Argonaute immune system. Nat Commun, 15:4852-4852, 2024 Cited by PubMed: 38844755DOI: 10.1038/s41467-024-49271-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.15 Å) |
Structure validation
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