8U1U
Structure of a class A GPCR/agonist complex
Summary for 8U1U
Entry DOI | 10.2210/pdb8u1u/pdb |
EMDB information | 41829 |
Descriptor | C-C motif chemokine 1,C-C chemokine receptor type 8,EGFP fusion protein, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total) |
Functional Keywords | gpcr, agonist, structural protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 202143.62 |
Authors | |
Primary citation | Sun, D.,Sun, Y.,Janezic, E.,Zhou, T.,Johnson, M.,Azumaya, C.,Noreng, S.,Chiu, C.,Seki, A.,Arenzana, T.L.,Nicoludis, J.M.,Shi, Y.,Wang, B.,Ho, H.,Joshi, P.,Tam, C.,Payandeh, J.,Comps-Agrar, L.,Wang, J.,Rutz, S.,Koerber, J.T.,Masureel, M. Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8. Nat Commun, 14:7940-7940, 2023 Cited by PubMed: 38040762DOI: 10.1038/s41467-023-43601-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
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