8U1L

Cryo-EM structure of the RAF1-HSP90-CDC37 complex in the closed state

8U1L の概要

• エントリーDOI: 10.2210/pdb8u1l/pdb
• EMDBエントリー: 41816 41817 41818
• 分子名称: Heat shock protein 83, RAF proto-oncogene serine/threonine-protein kinase, Hsp90 co-chaperone Cdc37, N-terminally processed, ... (5 entities in total)
• 機能のキーワード: craf, raf1, hsp90, cdc37, signaling protein-chaperone complex, signaling protein/chaperone
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 286351.05

構造登録者

Finci, L.I.,Simanshu, D.K. (登録日: 2023-09-01, 公開日: 2024-03-13)

• 主引用文献: Finci, L.I.,Chakrabarti, M.,Gulten, G.,Finney, J.,Grose, C.,Fox, T.,Yang, R.,Nissley, D.V.,McCormick, F.,Esposito, D.,Balius, T.E.,Simanshu, D.K.; Structural dynamics of RAF1-HSP90-CDC37 and HSP90 complexes reveal asymmetric client interactions and key structural elements.; Commun Biol, 7:260-260, 2024; PubMed: 38431713; DOI: 10.1038/s42003-024-05959-3

実験手法

ELECTRON MICROSCOPY (3.7 Å)