8TZI

Human equilibrative nucleoside transporter-1, JH-ENT-01 bound

Summary for 8TZI

• Entry DOI: 10.2210/pdb8tzi/pdb
• Descriptor: Equilibrative nucleoside transporter 1, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3-[4-[3-[3,4-dimethoxy-5-[[4-[oxidanyl(oxidanylidene)-$l^{4}-azanyl]phenyl]methoxy]phenyl]carbonyloxypropyl]-1,4-diazepan-1-yl]propyl 3,4,5-trimethoxybenzoate, ... (4 entities in total)
• Functional Keywords: adenosine transport, adenosine reuptake inhibitor, nucleoside, hent1, equilibrative nucleoside transporter, slc29, transport protein-inhibitor complex, transport protein/inhibitor
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 51729.74

Authors

Wright, N.J.,Lee, S.Y. (deposition date: 2023-08-26, release date: 2024-08-28)

• Primary citation: Wright, N.J.,Lee, S.Y.; Rational ENT1 inhibition as a pathway for neuropathic pain relief; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.7 Å)