8TYE

Lassa GPC (strain Josiah) bound to rabbit polyclonal fusion-peptide-targeting antibody FP-1

Summary for 8TYE

• Entry DOI: 10.2210/pdb8tye/pdb
• EMDB information: 41715
• Descriptor: Polyclonal Fv heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, Polyclonal Fv light chain, ... (10 entities in total)
• Functional Keywords: lassa virus glycoprotein complex, gpc, immune complex, antibody, polyclonal antibody, base antibody, viral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Lassa virus (strain Mouse/Sierra Leone/Josiah/1976); More
• Total number of polymer chains: 8
• Total formula weight: 252445.84

Authors

Perrett, H.R.,Brouwer, P.J.M.,Ward, A.B. (deposition date: 2023-08-25, release date: 2024-09-11, Last modification date: 2024-09-25)

• Primary citation: Brouwer, P.J.M.,Perrett, H.R.,Beaumont, T.,Nijhuis, H.,Kruijer, S.,Burger, J.A.,Bontjer, I.,Lee, W.H.,Ferguson, J.A.,Schauflinger, M.,Muller-Krauter, H.,Sanders, R.W.,Strecker, T.,van Gils, M.J.,Ward, A.B.; Defining bottlenecks and opportunities for Lassa virus neutralization by structural profiling of vaccine-induced polyclonal antibody responses.; Cell Rep, 43:114708-114708, 2024; PubMed: 39243373; DOI: 10.1016/j.celrep.2024.114708

Experimental method

ELECTRON MICROSCOPY (3.8 Å)