8TX5

Crystal structure of an engineered variant of galactose oxidase, GOaseRd4BB, from Fusarium graminearum

Summary for 8TX5

Entry DOI	10.2210/pdb8tx5/pdb
Descriptor	Galactose oxidase, COPPER (II) ION, GLYCEROL, ... (4 entities in total)
Functional Keywords	oxidoreductase, galactose oxidase, islatravir, aerobic oxidation, biocatalytic oxidation, (r)-ethynyl-glyceraldehyde 3-phosphate
Biological source	Fusarium graminearum
Total number of polymer chains	4
Total formula weight	278752.78
Authors	Selvaraj, B.,Orth, P. (deposition date: 2023-08-22, release date: 2024-07-03)
Primary citation	Shaw, M.H.,Fryszkowska, A.,Alvizo, O.,Attadgie, I.,Borra-Garske, M.,Devine, P.N.,Duan, D.,Grosser, S.T.,Forstater, J.H.,Hughes, G.J.,Maloney, K.M.,Margelefsky, E.,Mattern, K.A.,Miller, M.T.,Nawrat, C.C.,Nazor, J.,Orth, P.,Ouimet, C.M.,Robaire, S.A.,Ruccolo, S.,Schwalm, E.L.,Verma, D.,Xiao, L.,Selvaraj, B.,Zhang, V. Development of a Biocatalytic Aerobic Oxidation for the Manufacturing Route to Islatravir Chemrxiv, 2023 Cited by DOI: 10.26434/chemrxiv-2023-fg10l PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.93 Å)

Structure validation