8TX5

Crystal structure of an engineered variant of galactose oxidase, GOaseRd4BB, from Fusarium graminearum

8TX5 の概要

• エントリーDOI: 10.2210/pdb8tx5/pdb
• 分子名称: Galactose oxidase, COPPER (II) ION, GLYCEROL, ... (4 entities in total)
• 機能のキーワード: oxidoreductase, galactose oxidase, islatravir, aerobic oxidation, biocatalytic oxidation, (r)-ethynyl-glyceraldehyde 3-phosphate
• 由来する生物種: Fusarium graminearum
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 278752.78

構造登録者

Selvaraj, B.,Orth, P. (登録日: 2023-08-22, 公開日: 2024-07-03)

• 主引用文献: Shaw, M.H.,Fryszkowska, A.,Alvizo, O.,Attadgie, I.,Borra-Garske, M.,Devine, P.N.,Duan, D.,Grosser, S.T.,Forstater, J.H.,Hughes, G.J.,Maloney, K.M.,Margelefsky, E.,Mattern, K.A.,Miller, M.T.,Nawrat, C.C.,Nazor, J.,Orth, P.,Ouimet, C.M.,Robaire, S.A.,Ruccolo, S.,Schwalm, E.L.,Verma, D.,Xiao, L.,Selvaraj, B.,Zhang, V.; Development of a Biocatalytic Aerobic Oxidation for the Manufacturing Route to Islatravir; Chemrxiv, 2023; DOI: 10.26434/chemrxiv-2023-fg10l

実験手法

X-RAY DIFFRACTION (1.93 Å)