8TUD
IgG1 Fc Heterodimer combYSelect2
Summary for 8TUD
Entry DOI | 10.2210/pdb8tud/pdb |
Descriptor | Immunoglobulin gamma-1 heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total) |
Functional Keywords | igg1 fc, heterodimer, immune system |
Biological source | Homo sapiens x Mus musculus hybrid cell line More |
Total number of polymer chains | 2 |
Total formula weight | 55205.82 |
Authors | |
Primary citation | Azzam, T.,Du, J.J.,Flowers, M.W.,Ali, A.V.,Hunn, J.C.,Vijayvargiya, N.,Knagaram, R.,Bogacz, M.,Maravillas, K.E.,Sastre, D.E.,Fields, J.K.,Mirzaei, A.,Pierce, B.G.,Sundberg, E.J. Combinatorially restricted computational design of protein-protein interfaces to produce IgG heterodimers. Sci Adv, 10:eadk8157-eadk8157, 2024 Cited by PubMed: 38598628DOI: 10.1126/sciadv.adk8157 PDB entries with the same primary citation |
Experimental method |
Structure validation
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