8TUD

IgG1 Fc Heterodimer combYSelect2

8TUD の概要

• エントリーDOI: 10.2210/pdb8tud/pdb
• 分子名称: Immunoglobulin gamma-1 heavy chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• 機能のキーワード: igg1 fc, heterodimer, immune system
• 由来する生物種: Homo sapiens x Mus musculus hybrid cell line; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 55205.82

構造登録者

Azzam, T.,Du, J.J.,Sundberg, E.J. (登録日: 2023-08-16, 公開日: 2024-06-26)

• 主引用文献: Azzam, T.,Du, J.J.,Flowers, M.W.,Ali, A.V.,Hunn, J.C.,Vijayvargiya, N.,Knagaram, R.,Bogacz, M.,Maravillas, K.E.,Sastre, D.E.,Fields, J.K.,Mirzaei, A.,Pierce, B.G.,Sundberg, E.J.; Combinatorially restricted computational design of protein-protein interfaces to produce IgG heterodimers.; Sci Adv, 10:eadk8157-eadk8157, 2024; PubMed: 38598628; DOI: 10.1126/sciadv.adk8157

実験手法