8TTC

Structure of retromer VPS29-VPS35 (483-796) complexed with Fam21A repeat 20 (1289-1302)

8TTC の概要

• エントリーDOI: 10.2210/pdb8ttc/pdb
• 関連するPDBエントリー: 8TTA
• 分子名称: Vacuolar protein sorting-associated protein 29, Vacuolar protein sorting-associated protein 35, SER-ILE-PHE-ASP-ASP-ASP-MET-ASP-ASP-ILE-PHE-SER-SER-GLY, ... (8 entities in total)
• 機能のキーワード: vps29, vps35, fam21, retromer, wash complex, endosome, protein transport, endocytosis
• 由来する生物種: Mus musculus (house mouse); 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 115722.65

構造登録者

Chen, K.-E.,Guo, Q.,Collins, B.M. (登録日: 2023-08-13, 公開日: 2024-08-21)

• 主引用文献: Guo, Q.,Chen, K.E.,Gimenez-Andres, M.,Jellett, A.P.,Gao, Y.,Simonetti, B.,Liu, M.,Danson, C.M.,Heesom, K.J.,Cullen, P.J.,Collins, B.M.; Structural basis for coupling of the WASH subunit FAM21 with the endosomal SNX27-Retromer complex.; Proc.Natl.Acad.Sci.USA, 121:e2405041121-e2405041121, 2024; PubMed: 39116126; DOI: 10.1073/pnas.2405041121

実験手法

X-RAY DIFFRACTION (3.01 Å)