8TRQ
T cell recognition of citrullinated vimentin peptide presented by HLA-DR4
Summary for 8TRQ
Entry DOI | 10.2210/pdb8trq/pdb |
Descriptor | HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DRB1 beta chain, Vimentin, ... (8 entities in total) |
Functional Keywords | immune receptor complex, immune system |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 5 |
Total formula weight | 98549.40 |
Authors | Loh, T.J.,Lim, J.J.,Reid, H.H.,Rossjohn, J. (deposition date: 2023-08-10, release date: 2024-07-31, Last modification date: 2024-08-07) |
Primary citation | Loh, T.J.,Lim, J.J.,Jones, C.M.,Dao, H.T.,Tran, M.T.,Baker, D.G.,La Gruta, N.L.,Reid, H.H.,Rossjohn, J. The molecular basis underlying T cell specificity towards citrullinated epitopes presented by HLA-DR4. Nat Commun, 15:6201-6201, 2024 Cited by PubMed: 39043656DOI: 10.1038/s41467-024-50511-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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