8TLK
CDCA7 (Human) Binds Non-B-form 32-mer DNA oligo Containing a 5mC
Summary for 8TLK
Entry DOI | 10.2210/pdb8tlk/pdb |
Descriptor | Cell division cycle-associated protein 7, DNA (32-MER), ZINC ION, ... (7 entities in total) |
Functional Keywords | protein-dna complex, dna binding protein, zinc fingers, chromatin architecture, dna binding protein-dna complex, dna binding protein/dna |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 53291.16 |
Authors | |
Primary citation | Hardikar, S.,Ren, R.,Ying, Z.,Horton, J.R.,Bramble, M.D.,Liu, B.,Lu, Y.,Dan, J.,Zhang, X.,Cheng, X.,Chen, T. The ICF syndrome protein CDCA7 harbors a unique DNA-binding domain that recognizes a CpG dyad in the context of a non-B DNA Sci Adv, 2024 |
Experimental method | X-RAY DIFFRACTION (2.99 Å) |
Structure validation
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