8TK2
HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE (VHR) complexed with 2-((2,4-difluorobenzyl)amino)-2-oxoacetic acid
Summary for 8TK2
Entry DOI | 10.2210/pdb8tk2/pdb |
Descriptor | Dual specificity protein phosphatase 3, {[(2,4-difluorophenyl)methyl]amino}(oxo)acetic acid, DIMETHYL SULFOXIDE, ... (5 entities in total) |
Functional Keywords | protein dual-specificity phosphatase, vhr, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 41180.56 |
Authors | Aleshin, A.E.,Wu, J.,Lambert, L.J.,Cosford, N.D.P.,Tautz, L. (deposition date: 2023-07-25, release date: 2024-08-14) |
Primary citation | Aleshin, A.E.,Cosford, N.,Tautz, L. HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE (VHR) binding 2-((2,4-difluorobenzyl)amino)-2-oxoacetic acid To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
Download full validation report