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8TK2

HUMAN VH1-RELATED DUAL-SPECIFICITY PHOSPHATASE (VHR) complexed with 2-((2,4-difluorobenzyl)amino)-2-oxoacetic acid

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Dual specificity protein phosphatase 3polymer18320283.02UniProt (P51452)
Pfam (PF00782)
Homo sapiens (human)Dual specificity protein phosphatase VHR,Vaccinia H1-related phosphatase,VHR
2C, D
(A, B)
{[(2,4-difluorophenyl)methyl]amino}(oxo)acetic acidnon-polymer215.22Chemie (I1Y)
3E
(B)
DIMETHYL SULFOXIDEnon-polymer78.11Chemie (DMS)
4F
(B)
DI(HYDROXYETHYL)ETHERnon-polymer106.11Chemie (PEG)
5G, H
(A, B)
waterwater18.0240Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight40566.0
Non-Polymers*Number of molecules4
Total formula weight614.6
All*Total formula weight41180.6
*Water molecules are not included.

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PDB entries from 2025-06-18

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