8TH9
Structure of mammalian NEIL2 from Monodelphis domestica in complex with THF-containing DNA
Summary for 8TH9
Entry DOI | 10.2210/pdb8th9/pdb |
Descriptor | DNA-(apurinic or apyrimidinic site) lyase, DNA (5'-D(*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*TP*CP*CP*AP*(3DR)P*GP*TP*CP*TP*AP*C)-3'), ... (6 entities in total) |
Functional Keywords | neil2, dna glycosylase, dna lyase, lyase |
Biological source | Monodelphis domestica (gray short-tailed opossum) More |
Total number of polymer chains | 3 |
Total formula weight | 41132.00 |
Authors | Eckenroth, B.E.,Doublie, S. (deposition date: 2023-07-14, release date: 2023-11-01, Last modification date: 2023-12-27) |
Primary citation | Eckenroth, B.E.,Bumgarner, J.D.,Matsumoto-Elliott, O.,David, S.S.,Doublie, S. Structural and biochemical insights into NEIL2's preference for abasic sites. Nucleic Acids Res., 51:12508-12521, 2023 Cited by PubMed: 37971311DOI: 10.1093/nar/gkad1075 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.08 Å) |
Structure validation
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