8TH9

Structure of mammalian NEIL2 from Monodelphis domestica in complex with THF-containing DNA

8TH9 の概要

• エントリーDOI: 10.2210/pdb8th9/pdb
• 分子名称: DNA-(apurinic or apyrimidinic site) lyase, DNA (5'-D(*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*TP*CP*CP*AP*(3DR)P*GP*TP*CP*TP*AP*C)-3'), ... (6 entities in total)
• 機能のキーワード: neil2, dna glycosylase, dna lyase, lyase
• 由来する生物種: Monodelphis domestica (gray short-tailed opossum); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 41132.00

構造登録者

Eckenroth, B.E.,Doublie, S. (登録日: 2023-07-14, 公開日: 2023-11-01, 最終更新日: 2023-12-27)

• 主引用文献: Eckenroth, B.E.,Bumgarner, J.D.,Matsumoto-Elliott, O.,David, S.S.,Doublie, S.; Structural and biochemical insights into NEIL2's preference for abasic sites.; Nucleic Acids Res., 51:12508-12521, 2023; PubMed: 37971311; DOI: 10.1093/nar/gkad1075

実験手法

X-RAY DIFFRACTION (2.08 Å)