8TAB

RTA-PD00589

8TAB の概要

• エントリーDOI: 10.2210/pdb8tab/pdb
• 分子名称: Ricin A chain, CHLORIDE ION, 4H,5H-naphtho[1,2-b]thiophene-2-carboxylic acid, ... (6 entities in total)
• 機能のキーワード: n-glycosidase, inhibitor, toxin, hydrolase-inhibitor complex, hydrolase/inhibitor
• 由来する生物種: Ricinus communis (castor bean)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 29810.89

構造登録者

Rudolph, M.J.,Tumer, N. (登録日: 2023-06-27, 公開日: 2024-05-01)

• 主引用文献: Rudolph, M.J.,Dutta, A.,Tsymbal, A.M.,McLaughlin, J.E.,Chen, Y.,Davis, S.A.,Theodorous, S.A.,Pierce, M.,Algava, B.,Zhang, X.,Szekely, Z.,Roberge, J.Y.,Li, X.P.,Tumer, N.E.; Structure-based design and optimization of a new class of small molecule inhibitors targeting the P-stalk binding pocket of ricin.; Bioorg.Med.Chem., 100:117614-117614, 2024; PubMed: 38340640; DOI: 10.1016/j.bmc.2024.117614

実験手法

X-RAY DIFFRACTION (2.26 Å)