8T7C
Crystal structure of human phospholipase C gamma 2
Summary for 8T7C
Entry DOI | 10.2210/pdb8t7c/pdb |
Related | 8JQG 8JQH 8JQI |
Descriptor | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2, CALCIUM ION, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | phospholipase c gamma 2, autoinhibition, signaling, lipid metabolism, hydrolase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 1 |
Total formula weight | 136163.62 |
Authors | |
Primary citation | Shin, Y.,Plummer, A.M.,Mungenast, A.,Choi, H.,TenDyke, K.,Zhu, X.,Shepard, J.,Zhuang, N.,Hu, L.,Qian, D.,Wang, J.,Poda, S.,Liao, M.,Chen, Y. The crystal and cryo-EM structures of PLCg2 reveal dynamic inter-domain recognitions in autoinhibition To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.55 Å) |
Structure validation
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