8T5I
Crystal structure of human WDR5 in complex with MR4397
Summary for 8T5I
Entry DOI | 10.2210/pdb8t5i/pdb |
Descriptor | WD repeat-containing protein 5, N-[(2S)-1-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)-1-oxopentan-2-yl]-3-[(1H-imidazol-1-yl)methyl]benzamide, 1,2-ETHANEDIOL, ... (6 entities in total) |
Functional Keywords | wd-repeat, wdr, wdr5, sgc, transcription |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 70133.64 |
Authors | Kimani, S.,Dong, A.,Li, F.,Loppnau, P.,Ackloo, S.,Vedadi, M.,Brown, P.J.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.,Structural Genomics Consortium (SGC) (deposition date: 2023-06-13, release date: 2023-08-09, Last modification date: 2024-05-22) |
Primary citation | Kimani, S.,Dong, A.,Li, F.,Loppnau, P.,Ackloo, S.,Vedadi, M.,Brown, P.J.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.,Structural Genomics Consortium (SGC) Crystal structure of human WDR5 in complex with MR4397 To be published, |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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