8T5I

Crystal structure of human WDR5 in complex with MR4397

8T5I の概要

• エントリーDOI: 10.2210/pdb8t5i/pdb
• 分子名称: WD repeat-containing protein 5, N-[(2S)-1-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)-1-oxopentan-2-yl]-3-[(1H-imidazol-1-yl)methyl]benzamide, 1,2-ETHANEDIOL, ... (6 entities in total)
• 機能のキーワード: wd-repeat, wdr, wdr5, sgc, transcription
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 70133.64

構造登録者

Kimani, S.,Dong, A.,Li, F.,Loppnau, P.,Ackloo, S.,Vedadi, M.,Brown, P.J.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.,Structural Genomics Consortium (SGC) (登録日: 2023-06-13, 公開日: 2023-08-09, 最終更新日: 2024-05-22)

• 主引用文献: Kimani, S.,Dong, A.,Li, F.,Loppnau, P.,Ackloo, S.,Vedadi, M.,Brown, P.J.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.,Structural Genomics Consortium (SGC); Crystal structure of human WDR5 in complex with MR4397; To be published,

実験手法

X-RAY DIFFRACTION (1.7 Å)