8T5C
Lassa GPC Trimer in complex with Fab 8.11G and nanobody D5
8T5C の概要
エントリーDOI | 10.2210/pdb8t5c/pdb |
EMDBエントリー | 41048 |
分子名称 | Glycoprotein G1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (14 entities in total) |
機能のキーワード | vaccine, gpc, gp1, gp2, viral protein-immune system complex, viral protein/immune system |
由来する生物種 | Lassa virus Josiah 詳細 |
タンパク質・核酸の鎖数 | 11 |
化学式量合計 | 216540.92 |
構造登録者 | |
主引用文献 | Gorman, J.,Cheung, C.S.,Duan, Z.,Ou, L.,Wang, M.,Chen, X.,Cheng, C.,Biju, A.,Sun, Y.,Wang, P.,Yang, Y.,Zhang, B.,Boyington, J.C.,Bylund, T.,Charaf, S.,Chen, S.J.,Du, H.,Henry, A.R.,Liu, T.,Sarfo, E.K.,Schramm, C.A.,Shen, C.H.,Stephens, T.,Teng, I.T.,Todd, J.P.,Tsybovsky, Y.,Verardi, R.,Wang, D.,Wang, S.,Wang, Z.,Zheng, C.Y.,Zhou, T.,Douek, D.C.,Mascola, J.R.,Ho, D.D.,Ho, M.,Kwong, P.D. Cleavage-intermediate Lassa virus trimer elicits neutralizing responses, identifies neutralizing nanobodies, and reveals an apex-situated site-of-vulnerability. Nat Commun, 15:285-285, 2024 Cited by PubMed: 38177144DOI: 10.1038/s41467-023-44534-y 主引用文献が同じPDBエントリー |
実験手法 | ELECTRON MICROSCOPY (4.7 Å) |
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