8T3V

Cryo-EM structure of the DHA bound FFA1-Gq complex

8T3V の概要

• エントリーDOI: 10.2210/pdb8t3v/pdb
• EMDBエントリー: 41013
• 分子名称: Guanine nucleotide-binding protein G(q) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (7 entities in total)
• 機能のキーワード: gpcr, agonist, membrane protein
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 129092.80

構造登録者

Zhang, X.,Tikhonova, I.,Milligan, G.,Zhang, C. (登録日: 2023-06-07, 公開日: 2024-01-24)

• 主引用文献: Zhang, X.,Guseinov, A.A.,Jenkins, L.,Li, K.,Tikhonova, I.G.,Milligan, G.,Zhang, C.; Structural basis for the ligand recognition and signaling of free fatty acid receptors.; Sci Adv, 10:eadj2384-eadj2384, 2024; PubMed: 38198545; DOI: 10.1126/sciadv.adj2384

実験手法

ELECTRON MICROSCOPY (3.39 Å)