8T2M

Crystal structure of GABARAP in complex with the LIR of NSs4

8T2M の概要

• エントリーDOI: 10.2210/pdb8t2m/pdb
• 分子名称: Non-structural protein S,Gamma-aminobutyric acid receptor-associated protein chimera (2 entities in total)
• 機能のキーワード: rift valley fever virus, autophagy, lc3, gabarap, lir, protein binding
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 15192.23

構造登録者

Ali, M.G.H.,Wahba, H.M.,Cyr, N.,Omichinski, J.G. (登録日: 2023-06-06, 公開日: 2024-04-03)

• 主引用文献: Petraccione, K.,Ali, M.G.H.,Cyr, N.,Wahba, H.M.,Stocker, T.,Akhrymuk, M.,Akhrymuk, I.,Panny, L.,Bracci, N.,Cafaro, R.,Sastre, D.,Silberfarb, A.,O'Maille, P.,Omichinski, J.,Kehn-Hall, K.; An LIR motif in the Rift Valley fever virus NSs protein is critical for the interaction with LC3 family members and inhibition of autophagy.; Plos Pathog., 20:e1012093-e1012093, 2024; PubMed: 38512999; DOI: 10.1371/journal.ppat.1012093

実験手法

X-RAY DIFFRACTION (1.27 Å)