8T2L
Crystal structure of LC3A in complex with the LIR of NSs4
Summary for 8T2L
Entry DOI | 10.2210/pdb8t2l/pdb |
Descriptor | Non-structural protein S,Microtubule-associated proteins 1A/1B light chain 3A chimera (2 entities in total) |
Functional Keywords | rift valley fever virus, autophagy, lc3, gabarap, lir, protein binding |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 30859.07 |
Authors | Ali, M.G.H.,Wahba, H.M.,Cyr, N.,Omichinski, J.G. (deposition date: 2023-06-06, release date: 2024-04-03) |
Primary citation | Petraccione, K.,Ali, M.G.H.,Cyr, N.,Wahba, H.M.,Stocker, T.,Akhrymuk, M.,Akhrymuk, I.,Panny, L.,Bracci, N.,Cafaro, R.,Sastre, D.,Silberfarb, A.,O'Maille, P.,Omichinski, J.,Kehn-Hall, K. An LIR motif in the Rift Valley fever virus NSs protein is critical for the interaction with LC3 family members and inhibition of autophagy. Plos Pathog., 20:e1012093-e1012093, 2024 Cited by PubMed: 38512999DOI: 10.1371/journal.ppat.1012093 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.24 Å) |
Structure validation
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