8T26
Crystal Structure of Porphyromonas gingivalis Sialidase (PG_0352) D219A mutant bound to 3'-Sialyllactose (only Neu5Ac visible)
Summary for 8T26
Entry DOI | 10.2210/pdb8t26/pdb |
Related | 8FEB 8T1Y 8T1Z 8T24 |
Descriptor | Sialidase, putative, N-acetyl-alpha-neuraminic acid, DI(HYDROXYETHYL)ETHER, ... (6 entities in total) |
Functional Keywords | sialidase, neuraminidase, carbohydrate binding, virulence factor, hydrolase |
Biological source | Porphyromonas gingivalis |
Total number of polymer chains | 1 |
Total formula weight | 57390.23 |
Authors | Clark, N.D.,Malkowski, M.G. (deposition date: 2023-06-05, release date: 2023-10-04, Last modification date: 2023-10-11) |
Primary citation | Clark, N.D.,Pham, C.,Kurniyati, K.,Sze, C.W.,Coleman, L.,Fu, Q.,Zhang, S.,Malkowski, M.G.,Li, C. Functional and structural analyses reveal that a dual domain sialidase protects bacteria from complement killing through desialylation of complement factors. Plos Pathog., 19:e1011674-e1011674, 2023 Cited by PubMed: 37747935DOI: 10.1371/journal.ppat.1011674 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.42 Å) |
Structure validation
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