8T1Z
Crystal Structure of Porphyromonas gingivalis Sialidase (PG_0352) Bound to Neu5Ac (NANA)
Summary for 8T1Z
| Entry DOI | 10.2210/pdb8t1z/pdb |
| Related | 8FEB 8T1Y |
| Descriptor | Sialidase, N-acetyl-alpha-neuraminic acid, TRIETHYLENE GLYCOL, ... (6 entities in total) |
| Functional Keywords | sialidase, neuraminidase, carbohydrate binding, virulence factor, hydrolase |
| Biological source | Porphyromonas gingivalis |
| Total number of polymer chains | 1 |
| Total formula weight | 57704.59 |
| Authors | Clark, N.D.,Malkowski, M.G. (deposition date: 2023-06-05, release date: 2023-10-04, Last modification date: 2023-10-11) |
| Primary citation | Clark, N.D.,Pham, C.,Kurniyati, K.,Sze, C.W.,Coleman, L.,Fu, Q.,Zhang, S.,Malkowski, M.G.,Li, C. Functional and structural analyses reveal that a dual domain sialidase protects bacteria from complement killing through desialylation of complement factors. Plos Pathog., 19:e1011674-e1011674, 2023 Cited by PubMed: 37747935DOI: 10.1371/journal.ppat.1011674 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.93 Å) |
Structure validation
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