8T26
Crystal Structure of Porphyromonas gingivalis Sialidase (PG_0352) D219A mutant bound to 3'-Sialyllactose (only Neu5Ac visible)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Sialidase, putative | polymer | 509 | 56494.3 | 1 | UniProt (Q7MX62) Pfam (PF13088) | Porphyromonas gingivalis | |
| 2 | B (A) | N-acetyl-alpha-neuraminic acid | non-polymer | 309.3 | 1 | Chemie (SIA) | |||
| 3 | C (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 4 | D, E (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 2 | Chemie (PGE) | |||
| 5 | F (A) | beta-D-galactopyranose | non-polymer | 180.2 | 1 | Chemie (GAL) | |||
| 6 | G (A) | water | water | 18.0 | 489 | Chemie (HOH) |
Sequence modifications
A: 31 - 526 (UniProt: Q7MX62)
| PDB | External Database | Details |
|---|---|---|
| Met 18 | - | expression tag |
| Arg 19 | - | expression tag |
| Gly 20 | - | expression tag |
| Ser 21 | - | expression tag |
| His 22 | - | expression tag |
| His 23 | - | expression tag |
| His 24 | - | expression tag |
| His 25 | - | expression tag |
| His 26 | - | expression tag |
| His 27 | - | expression tag |
| Gly 28 | - | expression tag |
| Ser 29 | - | expression tag |
| Met 30 | - | expression tag |
| Ala 219 | Asp 219 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 56494.3 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 895.9 | |
| All* | Total formula weight | 57390.2 |
