8T25
Cryo-EM structure of the RBD-ACE2 interface of the SARS-CoV-2 trimeric spike protein bound to ACE2 receptor after local refinement at downRBD conformation.
Summary for 8T25
Entry DOI | 10.2210/pdb8t25/pdb |
EMDB information | 40980 |
Descriptor | Angiotensin-converting enzyme, Spike glycoprotein (2 entities in total) |
Functional Keywords | coronavirus, spike, ace2, mink, protein binding, viral protein |
Biological source | Neovison vison More |
Total number of polymer chains | 2 |
Total formula weight | 112745.75 |
Authors | Ahn, H.M.,Calderon, B.,Fan, X.,Gao, Y.,Horgan, N.,Zhou, B.,Liang, B. (deposition date: 2023-06-05, release date: 2023-10-25) |
Primary citation | Ahn, H.,Calderon, B.M.,Fan, X.,Gao, Y.,Horgan, N.L.,Jiang, N.,Blohm, D.S.,Hossain, J.,Rayyan, N.W.K.,Osman, S.H.,Lin, X.,Currier, M.,Steel, J.,Wentworth, D.E.,Zhou, B.,Liang, B. Structural basis of the American mink ACE2 binding by Y453F trimeric spike glycoproteins of SARS-CoV-2. J Med Virol, 95:e29163-e29163, 2023 Cited by PubMed: 37842796DOI: 10.1002/jmv.29163 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.62 Å) |
Structure validation
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