8T0D

Crystal structure of integrin beta-2 tail bound to the FERM-folded talin head domain with E269A/Y270A/K306Q triple mutation

Summary for 8T0D

Entry DOI	10.2210/pdb8t0d/pdb
Related	8FSE 8FTB 8T0A
Descriptor	Integrin beta-2,Talin-1 (2 entities in total)
Functional Keywords	talin, integrin, beta-2, cell adhesion
Biological source	Mus musculus (house mouse) More
Total number of polymer chains	1
Total formula weight	47255.29
Authors	Wu, J.,Gao, T. (deposition date: 2023-05-31, release date: 2024-07-03)
Primary citation	Gao, T.,Kabir, S.,Wu, J. Structure of Talin Bound to beta 2 Integrin Unveils the Molecular Mechanism of Species-Specific Integrin Activation Biorxiv, 2024 Cited by DOI: 10.1101/2024.05.28.596271 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.77 Å)

Structure validation