8T0D
Crystal structure of integrin beta-2 tail bound to the FERM-folded talin head domain with E269A/Y270A/K306Q triple mutation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Integrin beta-2,Talin-1 | polymer | 411 | 47255.3 | 1 | UniProt (P11835) UniProt (P26039) Pfam (PF16511) Pfam (PF00373) Pfam (PF02174) | Mus musculus (house mouse) | Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta,Complement receptor C3 subunit beta |
| 2 | B (A) | water | water | 18.0 | 45 | Chemie (HOH) |
Sequence modifications
A: -9 - 0 (UniProt: P11835)
A: 1 - 430 (UniProt: P26039)
| PDB | External Database | Details |
|---|---|---|
| Met -10 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| - | Asp 139 | deletion |
| - | Glu 140 | deletion |
| - | Gly 141 | deletion |
| - | Thr 142 | deletion |
| - | Gly 143 | deletion |
| - | Thr 144 | deletion |
| - | Leu 145 | deletion |
| - | Arg 146 | deletion |
| - | Lys 147 | deletion |
| - | Asp 148 | deletion |
| - | Lys 149 | deletion |
| - | Thr 150 | deletion |
| - | Leu 151 | deletion |
| - | Leu 152 | deletion |
| - | Arg 153 | deletion |
| - | Asp 154 | deletion |
| - | Glu 155 | deletion |
| - | Lys 156 | deletion |
| - | Lys 157 | deletion |
| - | Met 158 | deletion |
| - | Glu 159 | deletion |
| - | Lys 160 | deletion |
| - | Leu 161 | deletion |
| - | Lys 162 | deletion |
| - | Gln 163 | deletion |
| - | Lys 164 | deletion |
| - | Leu 165 | deletion |
| - | His 166 | deletion |
| - | Thr 167 | deletion |
| - | Asp 168 | deletion |
| Ala 269 | Glu 269 | engineered mutation |
| Ala 270 | Tyr 270 | engineered mutation |
| Gln 306 | Lys 306 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 47255.3 | |
| All* | Total formula weight | 47255.3 |
