8SZL
Human liver-type glutaminase (Apo form)
Summary for 8SZL
Entry DOI | 10.2210/pdb8szl/pdb |
EMDB information | 40920 |
Descriptor | Glutaminase liver isoform, mitochondrial (1 entity in total) |
Functional Keywords | metabolic, cancer, hydrolase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 265638.88 |
Authors | Feng, S.,Aplin, C.,Nguyen, T.-T.T.,Milano, S.K.,Cerione, R.A. (deposition date: 2023-05-30, release date: 2024-03-13) |
Primary citation | Feng, S.,Aplin, C.,Nguyen, T.T.,Milano, S.K.,Cerione, R.A. Filament formation drives catalysis by glutaminase enzymes important in cancer progression. Nat Commun, 15:1971-1971, 2024 Cited by PubMed: 38438397DOI: 10.1038/s41467-024-46351-3 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.12 Å) |
Structure validation
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