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8SWQ

Structure of K. lactis PNP bound to transition state analog DADMe-IMMUCILLIN H and sulfate

Summary for 8SWQ
Entry DOI10.2210/pdb8swq/pdb
Related8SWP 8SWR 8SWS 8SWT 8SWU
DescriptorPurine nucleoside phosphorylase, 7-[[(3R,4R)-3-(hydroxymethyl)-4-oxidanyl-pyrrolidin-1-ium-1-yl]methyl]-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one, SULFATE ION, ... (5 entities in total)
Functional Keywordspentosyltransferase, purine nucleoside phosphorylase, transferase
Biological sourceKluyveromyces lactis NRRL Y-1140
Total number of polymer chains6
Total formula weight204383.61
Authors
Fedorov, E.,Ghosh, A. (deposition date: 2023-05-19, release date: 2023-10-18, Last modification date: 2023-11-22)
Primary citationMinnow, Y.V.T.,Schramm, V.L.,Almo, S.C.,Ghosh, A.
Phosphate Binding in PNP Alters Transition-State Analogue Affinity and Subunit Cooperativity.
Biochemistry, 62:3116-3125, 2023
Cited by
PubMed: 37812583
DOI: 10.1021/acs.biochem.3c00264
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.979 Å)
Structure validation

225681

건을2024-10-02부터공개중

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