8SWJ

Co-crystal structure of 53BP1 tandem Tudor domains in complex with UNC8531

Summary for 8SWJ

• Entry DOI: 10.2210/pdb8swj/pdb
• Descriptor: TP53-binding protein 1, (3S)-N-(4'-carbamoyl[1,1'-biphenyl]-3-yl)-1-[4-(4-methylpiperazin-1-yl)pyridine-2-carbonyl]piperidine-3-carboxamide, UNKNOWN ATOM OR ION, ... (4 entities in total)
• Functional Keywords: 53bp1, tudor domain, tumor suppressor, tp53-binding protein 1, sgc, structural genomics, psi-2, protein structure initiative, structural genomics consortium, transcription
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 58594.09

Authors

Zeng, H.,Dong, A.,Shell, D.J.,Foley, C.,Pearce, K.H.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.,Structural Genomics Consortium (SGC) (deposition date: 2023-05-18, release date: 2023-08-02)

• Primary citation: Zeng, H.,Dong, A.,Shell, D.J.,Foley, C.,Pearce, K.H.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.; Co-crystal structure of 53BP1 tandem Tudor domains in complex with UNC8531; To be published,

Experimental method

X-RAY DIFFRACTION (1.6 Å)