8SWA
Crystal structure of the human S-adenosylmethionine synthetase 1 in complex with SAM and PPNP
Summary for 8SWA
Entry DOI | 10.2210/pdb8swa/pdb |
Descriptor | S-adenosylmethionine synthase isoform type-1, (DIPHOSPHONO)AMINOPHOSPHONIC ACID, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | complex, 1-carbon, sam, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 45580.20 |
Authors | |
Primary citation | Pham, V.N.,Bruemmer, K.J.,Toh, J.D.W.,Ge, E.J.,Tenney, L.,Ward, C.C.,Dingler, F.A.,Millington, C.L.,Garcia-Prieto, C.A.,Pulos-Holmes, M.C.,Ingolia, N.T.,Pontel, L.B.,Esteller, M.,Patel, K.J.,Nomura, D.K.,Chang, C.J. Formaldehyde regulates S -adenosylmethionine biosynthesis and one-carbon metabolism. Science, 382:eabp9201-eabp9201, 2023 Cited by PubMed: 37917677DOI: 10.1126/science.abp9201 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.999 Å) |
Structure validation
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