8SW9

Plasmodium falciparum M17 (A460S) mutant

8SW9 の概要

• エントリーDOI: 10.2210/pdb8sw9/pdb
• 分子名称: Leucine aminopeptidase, ZINC ION, CARBONATE ION, ... (6 entities in total)
• 機能のキーワード: metallo-exopeptidase, m17 aminopeptidase, leucine aminopeptidase, malaria, aminopeptidase, hydrolase
• 由来する生物種: Plasmodium falciparum (malaria parasite P. falciparum)
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 713388.23

構造登録者

McGowan, S.,Suraweera, C.,Drinkwater, N. (登録日: 2023-05-17, 公開日: 2024-04-24)

• 主引用文献: de Koning-Ward, T.F.,Drinkwater, N.,Edgar, R.C.S.,McGowan, S.,Scammells, P.J.; Characterisation of a novel antimalarial agent targeting haemaglobin digestion that shows cross-species reactivity and excellent in vivo properties.; Mbio, 2024

実験手法

X-RAY DIFFRACTION (2.6 Å)