8SUR
TMEM16F bound with Niclosamide
Summary for 8SUR
Entry DOI | 10.2210/pdb8sur/pdb |
EMDB information | 40776 |
Descriptor | Anoctamin-6, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | ca2+-activated ion channels and lipid scramblases, membrane protein |
Biological source | Mus musculus (mouse) |
Total number of polymer chains | 2 |
Total formula weight | 214775.39 |
Authors | |
Primary citation | Feng, S.,Puchades, C.,Ko, J.,Wu, H.,Chen, Y.,Figueroa, E.E.,Gu, S.,Han, T.W.,Ho, B.,Cheng, T.,Li, J.,Shoichet, B.,Jan, Y.N.,Cheng, Y.,Jan, L.Y. Identification of a drug binding pocket in TMEM16F calcium-activated ion channel and lipid scramblase. Nat Commun, 14:4874-4874, 2023 Cited by PubMed: 37573365DOI: 10.1038/s41467-023-40410-x PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
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