8SSP

AurA bound to danusertib and activating monobody Mb1

Summary for 8SSP

• Entry DOI: 10.2210/pdb8ssp/pdb
• Descriptor: Aurora kinase A, Mb1, 1,2-ETHANEDIOL, ... (9 entities in total)
• Functional Keywords: complex, kinase, monobody, transferase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 44824.59

Authors

Ludewig, H.,Kim, C.,Kern, D. (deposition date: 2023-05-08, release date: 2023-09-06)

• Primary citation: Kim, C.,Ludewig, H.,Hadzipasic, A.,Kutter, S.,Nguyen, V.,Kern, D.; A biophysical framework for double-drugging kinases.; Proc.Natl.Acad.Sci.USA, 120:e2304611120-e2304611120, 2023; PubMed: 37590418; DOI: 10.1073/pnas.2304611120

Experimental method

X-RAY DIFFRACTION (2.6 Å)