8SOJ
Cryo-EM structure of human CST bound to POT1(ESDL)/TPP1 in the absence of telomeric ssDNA
Summary for 8SOJ
Entry DOI | 10.2210/pdb8soj/pdb |
EMDB information | 40659 |
Descriptor | CST complex subunit CTC1, CST complex subunit STN1, CST complex subunit TEN1, ... (5 entities in total) |
Functional Keywords | telomere, shelterin, cst, complex, dna binding protein |
Biological source | Escherichia coli O157:H7 More |
Total number of polymer chains | 4 |
Total formula weight | 380868.87 |
Authors | Cai, S.W. (deposition date: 2023-04-28, release date: 2023-06-07, Last modification date: 2024-10-16) |
Primary citation | Cai, S.W.,Takai, H.,Zaug, A.J.,Dilgen, T.C.,Cech, T.R.,Walz, T.,de Lange, T. POT1 recruits and regulates CST-Pol alpha /primase at human telomeres. Cell, 187:3638-3651.e18, 2024 Cited by PubMed: 38838667DOI: 10.1016/j.cell.2024.05.002 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
Download full validation report