8SMG

Structure of SPO1 phage Tad2 in complex with 1''-2' gcADPR

Summary for 8SMG

• Entry DOI: 10.2210/pdb8smg/pdb
• Descriptor: Gp34.65, (1S,3R,4R,6R,9S,11R,14R,15S,16R,18R)-4-(6-amino-9H-purin-9-yl)-9,11,15,16,18-pentahydroxy-2,5,8,10,12,17-hexaoxa-9lambda~5~,11lambda~5~-diphosphatricyclo[12.2.1.1~3,6~]octadecane-9,11-dione (3 entities in total)
• Functional Keywords: gcadpr, thoeris, anti-phage, viral protein
• Biological source: Okubovirus
• Total number of polymer chains: 2
• Total formula weight: 20792.26

Authors

Lu, A.,Yirmiya, E.,Leavitt, A.,Avraham, C.,Osterman, I.,Garb, J.,Antine, S.P.,Mooney, S.E.,Hobbs, S.J.,Amitai, G.,Sorek, R.,Kranzusch, P.J. (deposition date: 2023-04-26, release date: 2023-11-22, Last modification date: 2024-01-24)

• Primary citation: Yirmiya, E.,Leavitt, A.,Lu, A.,Ragucci, A.E.,Avraham, C.,Osterman, I.,Garb, J.,Antine, S.P.,Mooney, S.E.,Hobbs, S.J.,Kranzusch, P.J.,Amitai, G.,Sorek, R.; Phages overcome bacterial immunity via diverse anti-defence proteins.; Nature, 625:352-359, 2024; PubMed: 37992756; DOI: 10.1038/s41586-023-06869-w

Experimental method

X-RAY DIFFRACTION (2.1 Å)