8SHV

38B7 unliganded

Summary for 8SHV

• Entry DOI: 10.2210/pdb8shv/pdb
• Descriptor: 38B7 light chain, 38B7 heavy chain, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (4 entities in total)
• Functional Keywords: allergy, peanut, antibody, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 47718.09

Authors

Spiller, B.W.,Shrem, R.A. (deposition date: 2023-04-14, release date: 2024-12-25, Last modification date: 2025-01-29)

Primary citation

Smith, S.A.,Shrem, R.A.,Lanca, B.B.C.,Zhang, J.,Wong, J.J.W.,Croote, D.,Peebles Jr., R.S.,Spiller, B.W.
Structural determinants of peanut induced anaphylaxis.
J.Allergy Clin.Immunol., 2025

PubMed Abstract: Human monoclonal IgE antibodies recognizing peanut allergens have recently become available, but we lack a detailed understanding of how these IgEs target allergens.

PubMed: 39805366
DOI: 10.1016/j.jaci.2024.12.1095

Experimental method

X-RAY DIFFRACTION (1.58 Å)