8SCB

Terminating ribosome with SRI-41315

This is a non-PDB format compatible entry.

Summary for 8SCB

• Entry DOI: 10.2210/pdb8scb/pdb
• EMDB information: 40344
• Descriptor: Ribosomal protein L8, 60S ribosomal protein L11, eL13, ... (92 entities in total)
• Functional Keywords: termination, sri-41315, ribosome
• Biological source: Homo sapiens; More
• Total number of polymer chains: 87
• Total formula weight: 3615287.80

Authors

Yip, M.C.J.,Coelho, J.P.L.,Oltion, K.,Tauton, J.,Shao, S. (deposition date: 2023-04-05, release date: 2023-12-27, Last modification date: 2024-07-17)

• Primary citation: Coelho, J.P.L.,Yip, M.C.J.,Oltion, K.,Taunton, J.,Shao, S.; The eRF1 degrader SRI-41315 acts as a molecular glue at the ribosomal decoding center.; Nat.Chem.Biol., 20:877-884, 2024; PubMed: 38172604; DOI: 10.1038/s41589-023-01521-0

Experimental method

ELECTRON MICROSCOPY (2.5 Å)