8SCA

Rec3 Domain from S. pyogenes Cas9

Summary for 8SCA

Entry DOI	10.2210/pdb8sca/pdb
Descriptor	CRISPR-associated endonuclease Cas9/Csn1, 1,2-ETHANEDIOL (3 entities in total)
Functional Keywords	crispr cas9, nucleic acid binding protein, rna binding protein
Biological source	Streptococcus pyogenes
Total number of polymer chains	1
Total formula weight	26130.97
Authors	D'Ordine, A.M.,Skeens, E.,Lisi, G.P.,Jogl, G. (deposition date: 2023-04-05, release date: 2024-03-13)
Primary citation	Skeens, E.,Sinha, S.,Ahsan, M.,D'Ordine, A.M.,Jogl, G.,Palermo, G.,Lisi, G.P. High-fidelity, hyper-accurate, and evolved mutants rewire atomic-level communication in CRISPR-Cas9. Sci Adv, 10:eadl1045-eadl1045, 2024 Cited by PubMed: 38446895 DOI: 10.1126/sciadv.adl1045 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.67 Å)

Structure validation