8SBI

Crystal structure of human sterol 14 alpha-demethylase (CYP51) in the ligand-free state

Summary for 8SBI

• Entry DOI: 10.2210/pdb8sbi/pdb
• Descriptor: Lanosterol 14-alpha demethylase, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total)
• Functional Keywords: monooxygenase, cytochrome p450, endoplasmic reticulum, sterol biosynthesis, oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 104587.68

Authors

Hargrove, T.Y.,Wawrzak, Z.,Lepesheva, G.I. (deposition date: 2023-04-03, release date: 2023-04-12, Last modification date: 2024-05-22)

• Primary citation: Hargrove, T.Y.,Wawrzak, Z.,Lepesheva, G.I.; Structural dynamics of sterol 14 alpha demethylases upon catalysis; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.73 Å)